The European Medicines Agency (EMA, for its acronym in English) has authorized this Thursday the vaccine against . A new medicine that will be a shock to the vaccination plan because the European Union bought 200 million doses (10% for Spain), which the pharmaceutical company will deliver throughout this year. The Ministry of Health expects that 8 million doses will arrive next quarter.
What is Johnson & Johnson’s Janssen vaccine like?
The Janssen Covid-19 vaccine, unlike Pfizer’s or Moderna’s, is manufactured using the adenovirus type 26 (Ad26), which is modified to deliver part of its genetic material to the cells of the human body so that they begin to produce the S protein, which acts against SARS-CoV-2.
Ad26, which can cause cold symptoms and conjunctivitis, is modified in the vaccine so that it cannot replicate in the human body and cause disease. This laboratory also used this system to develop its experimental vaccines against Zika, RSV and HIV.
Beyond the composition, the most important advantages of the Janssen vaccine are that it only requires one dose and that it is stable in storage at 2/8 degrees Celsius for three months and at -20 degrees for two years.
Efficacy of Johnson & Johnson’s Janssen vaccine against Covid-19
On March 1, the American Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for the distribution of the Covid-19 vaccine developed by Janssen for people over 18 years old.
The FDA authorization states that the vaccine has been approximately 67% effective in preventing the onset of moderate to severe/critical Covid-19 at least 14 days after vaccination and 66% effective in preventing the onset of COVID-19. moderate to severe/critical disease at 28 days after vaccination.
However, the vaccine is 77% effective in preventing the appearance of severe/critical Covid-19 at 14 days, and 85% at 28 days. Currently, as reported by the FDA, there is no data available to determine how long the vaccine will provide protection, nor is there evidence that the vaccine prevents person-to-person transmission of SARS-CoV-2.
Side effects of Johnson & Johnson’s Janssen vaccine against Covid-19
Centers for Disease Control and Prevention (CDC) explains that those in the Johnson & Johnson vaccine:
1. Side effects at the injection site: pain, redness, and swelling.
The FDA document reports that 50.2% of those vaccinated reported side effects at the injection site, with pain being the most frequent. In addition, all local adverse reactions were reported more frequently in the young (18-59 years) than in those older than 60 years.
2. Side effects throughout the body: tiredness, headache, muscle pain, chills, fever, and nausea.
He explains that 55.1% of those vaccinated reported adverse reactions and the most frequent were headache and fatigue. In addition, the US body notes that systemic side effects were reported more frequently among younger participants (18-59 years) than those older than 60 years. However, nausea was common in both groups.
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