There are more and more to the entire population. A position that would allow to vaccinate all individuals under 60 years of age who received the first puncture after the Ministry of Health made the decision not to administer it.
What immunity does the first dose of AstraZeneca offer?
The latest assessment by the European Medicines Agency (EMA) showed that the first dose of the vaccine offers 80% immunity over a period of four months. In addition, it was in favor of continuing to administer a second dose of AstraZeneca between 4 and 12 weeks after administering the first, as suggested in the product information.
In this new report, carried out by the Committee for Medicinal Products for Human Use (CHMP), it also looked at the possibility of increasing the dosing interval, of avoiding the administration of a second dose or of administering a second dose with a vaccine of messenger RNA. However, the agency concluded that there were insufficient data to determine whether the risk of thrombosis after a second dose varies from the risk after administration of the first. In the absence of these data, the CHMP has not made any recommendations other than those already made in the AstraZeneca SmPC.
Administering the second dose with AstraZeneca is not a possibility that Sanidad contemplates
Despite requests from some autonomous communities, the Ministry of Health does not contemplate administering doses of AstraZeneca in those under 60 years of age. In fact, the study being carried out at the Carlos III Institute in Madrid The goal of Combivac, the name of the study, is to conclude whether it is better not to administer more doses in individuals who received the first from AstraZeneca or to inject a second Pfizer dosage.
When will the Government decide what to do with those vaccinated with AstraZeneca under 60 years of age
The Combivacs study will include 600 people randomly selected from those who have received a dose of AstraZeneca’s vaccine, provided that a minimum of 8 weeks have elapsed since that dose until the start of the trial and they are under 60 years of age.
In the trial, volunteers will be randomly divided into two groups. Group 1 or intervention group will consist of 400 people and will receive one dose of the Pfizer vaccine, followed by 28 days of clinical observation and antibody testing for one year. For its part, group 2 will consist of 200 people, who will not initially receive any vaccine. This group 2 will act as a control group.
The comparison of immune response between the two groups will be carried out on analyzes obtained 14 days after the inclusion of each volunteer, without prejudice to other very exhaustive analyzes that will be carried out over a year. The Government hopes to have the first results five weeks after the start of the trial, that is, at the end of May or the beginning of June.
Facebook Comments
Disqus